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Dexmedetomidine decreases opioid requirements and facilitates ventilator weaning in neonates

May 26, 2026

IV paracetamol (acetaminophen) can cut 48-hour morphine exposure by 79% after cardiac surgery

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Bayesian vancomycin dosing hits target in 100% of neonates

May 19, 2026

A single sample ≥ 5 hours after the first dose accurately predicts AUC for neonatal vancomycin

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Symptom-based opioid dosing cut NOWS discharge time by 2.3 days

May 12, 2026

FDA expands Stelara approval to children 2+ with moderately to severely active Crohn's disease

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Expectant PDA management cut mortality from 9.6% to 4.1% in preemies

May 5, 2026

Vancomycin and gentamicin are the antibiotics most commonly implicated in neonatal AKI

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2026 Surviving Sepsis pediatric guideline: what changed

Apr 28, 2026

Ceftriaxone displaces bilirubin from albumin binding sites and can raise free bilirubin in neonates

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2026 ADA Standards expand SGLT2i options for pediatric type 2 diabetes

Apr 21, 2026

Nearly 25% of children in LMICs experience Shigella diarrhea requiring medical attention by age 2.

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Pediatric empyema: 2026 IDSA/PIDS CAP guideline favors fibrinolytics over VATS

Apr 14, 2026

FDA alerts clinicians to undeclared DMAA, DMHA, and phenibut in Addall supplements

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New PALS diastolic BP targets during pediatric CPR

Apr 7, 2026

Cefepime is preferred over ceftazidime when a cephalosporin is needed for neonatal sepsis or meningitis

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Surfactant didn't shorten ventilation in infant bronchiolitis (BESS trial)

Mar 31, 2026

~89,000 bottles of Children's Ibuprofen recalled after reports of foreign particles

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Tirzepatide cuts HbA1c by 2.23% in youth-onset type 2 diabetes

Mar 24, 2026

Federal court restores pre-January 2026 pediatric vaccine schedule

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Pediatric Pearls

Clinical insights for neonatal & pediatric care.

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