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Oliver Buchannon
Dr. Susannah F. Vanderpool

Neonatal & Pediatric Clinical Pharmacist

Surfactant didn't shorten ventilation in infant bronchiolitis (BESS trial)

Mar 31, 2026

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1 min read

Surfactant didn't shorten ventilation in infant bronchiolitis (BESS trial)

~89,000 bottles of Children's Ibuprofen recalled after reports of foreign particles

Dr. Susannah F. Vanderpool
Dr. Susannah F. Vanderpool
Tirzepatide cuts HbA1c by 2.23% in youth-onset type 2 diabetes

Mar 24, 2026

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1 min read

Tirzepatide cuts HbA1c by 2.23% in youth-onset type 2 diabetes

Federal court restores pre-January 2026 pediatric vaccine schedule

Dr. Susannah F. Vanderpool
Dr. Susannah F. Vanderpool
Clinical Insights - Mar 17, 2026

Mar 17, 2026

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4 min read

Clinical Insights - Mar 17, 2026

Nearly 20,000 U.S. emergency department visits occur each year for oral prescription medication ingestions in children younger than 6 years. Clonidine and buprenorphine account for the highest hospitalization estimates.

Dr. Susannah F. Vanderpool
Dr. Susannah F. Vanderpool
Clinical Insights - Mar 10, 2026

Mar 10, 2026

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4 min read

Clinical Insights - Mar 10, 2026

A 10-day hydrocortisone taper given at 14-28 days of life in ventilated preterm infants did not significantly impact functional outcomes at early school age compared with placebo.

Dr. Susannah F. Vanderpool
Dr. Susannah F. Vanderpool
Clinical Insights - Mar 3, 2026

Mar 3, 2026

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4 min read

Clinical Insights - Mar 3, 2026

Six weeks of once-daily intranasal saline resolved symptoms in 29.5% of children 3-12 years old, with cumulative resolution near 50% after 12 weeks. Adding mometasone after nonresponse did not improve outcomes.

Dr. Susannah F. Vanderpool
Dr. Susannah F. Vanderpool
Clinical Insights - Feb 24, 2026

Feb 24, 2026

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4 min read

Clinical Insights - Feb 24, 2026

In 44 pediatric cardiac patients 0-24 months of age (median 2.1 months), the median clopidogrel dose associated with therapeutic P2Y12 reaction unit (PRU) values was 0.22 mg/kg/day (IQR 0.19-0.34). This conflicts with the fixed 0.2 mg/kg/day recommended by the PICOLO trial.

Dr. Susannah F. Vanderpool
Dr. Susannah F. Vanderpool
Clinical Insights - Feb 17, 2026

Feb 17, 2026

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4 min read

Clinical Insights - Feb 17, 2026

Explainable machine learning models achieved higher simulated therapeutic alignment than standard weight-based dosing in young children, though findings remain exploratory.

Dr. Susannah F. Vanderpool
Dr. Susannah F. Vanderpool
Clinical Insights - Feb 10, 2026

Feb 10, 2026

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5 min read

Clinical Insights - Feb 10, 2026

Percentage of term and late-preterm infants who did not receive vitamin K in the U.S. increased from 2.9% to 5.2% between 2017 and 2024, with refusal trends beginning prior to the COVID-19 pandemic.

Dr. Susannah F. Vanderpool
Dr. Susannah F. Vanderpool
Clinical Insights - Feb 3, 2026

Feb 3, 2026

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5 min read

Clinical Insights - Feb 3, 2026

Pediatric practice is shifting from trough-based monitoring to AUC/MIC targets of 400-600 mg·h/L, with higher initial doses and earlier monitoring to optimize exposure and reduce nephrotoxicity.

Dr. Susannah F. Vanderpool
Dr. Susannah F. Vanderpool
Clinical Insights - Jan 27, 2026

Jan 27, 2026

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4 min read

Clinical Insights - Jan 27, 2026

Propranolol, esmolol, and captopril were the most commonly used agents in preterm neonates, with dosing strategies varying by gestational age and clinical stability.

Dr. Susannah F. Vanderpool
Dr. Susannah F. Vanderpool
Clinical Insights - Jan 20, 2026

Jan 20, 2026

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4 min read

Clinical Insights - Jan 20, 2026

Placebo minitablets mixed with soft food are acceptable for many children 9 months to 7 years, with swallowability improving with age and higher soft-food volumes often preferred.

Dr. Susannah F. Vanderpool
Dr. Susannah F. Vanderpool
Clinical Insights - Jan 13, 2026

Jan 13, 2026

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4 min read

Clinical Insights - Jan 13, 2026

Intramuscular aluminum forms a slow-release depot and is efficiently renally cleared, with no detectable rise in serum aluminum levels and no credible association with autism, asthma, or autoimmune disease.

Dr. Susannah F. Vanderpool
Dr. Susannah F. Vanderpool
Clinical Insights - Jan 6, 2026

Jan 6, 2026

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4 min read

Clinical Insights - Jan 6, 2026

2025 updates include higher endotracheal epinephrine dosing while access is obtained, mandate a fixed saline flush, and formally recognize IO access.

Dr. Susannah F. Vanderpool
Dr. Susannah F. Vanderpool

Pediatric Pearls

Clinical insights for neonatal & pediatric care.

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