Clinical Insights - Feb 24, 2026
In 44 pediatric cardiac patients 0-24 months of age (median 2.1 months), the median clopidogrel dose associated with therapeutic P2Y12 reaction unit (PRU) values was 0.22 mg/kg/day (IQR 0.19-0.34). This conflicts with the fixed 0.2 mg/kg/day recommended by the PICOLO trial.
